Kastamonu Medical Journal regularly publishes internationally qualified issues in the field of Medicine in the light of up-to-date information.

Original Article
Investigation of some trace element levels in multiple sclerosis
Aims: In this study, it was aimed to investigate the relationship between multiple sclerosis (MS) and the homeostatic state of trace elements, and to reveal the relationship between Fe and Zn in MS pathology.
Methods: Total of 40 (20 patients and 20 control) subjects were participated to this study. Blood samples were taken and analysed plasma iron and zinc levels using an atomic Absorption Spectrophotometer. Kolmogrow-Smirnov Z test used to analyse statistically significance of the data. P<0.05 was accepted as significant.
Results: The plasma iron and Zn levels were found to be significantly lower in MS patients compared to control.
Conclusion: Considering the important beneficial effects of iron and zinc against neurodegenerative disease and increased oxidative stress, reduced level of these trace elements should be considered in MS treatment.

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Volume 1, Issue 1, 2021
Page : 1-4