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Kastamonu Medical Journal

Kastamonu Medical Journal regularly publishes internationally qualified issues in the field of Medicine in the light of up-to-date information.

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Original Article
Determine the relationship between the severity of trauma and plasma amino acid levels in patients presenting to the emergency department after isolated thoracic trauma
Abstract
Aims: Trauma represents a significant health concern that can affect individuals across the lifespan. To anticipate the outcomes of thoracic trauma, a chest trauma severity score (TTSS) has been established for use in patients presenting with traumatic injuries. The relationship between TTSS and amino acid (aa) levels in patients remains to be elucidated.
Methods: The current study included a prospective cohort of 35 patients presenting to the emergency department with isolated thoracic trauma between October 2022 and October 2023. A control group of 35 individuals with similar age and gender characteristics was also included. The TTSS of the patient group was calculated at the time of presentation. The alterations in amino acid levels associated with TTSS were assessed in the blood samples obtained from the patient and control groups.
Results: Serum arginine levels of patients with isolated thoracic trauma exhibited a lower correlation at the time of initial presentation compared to the control group. However, at 48 hours, these levels were observed to be higher (p<0.044, p<0.040). The serum levels of glycine and taurine amino acids were observed to be higher in the initial presentation of patients compared to the control group (p<0.041, p<0.016). A total of 35 patients admitted to the emergency department with isolated thoracic trauma between October 2022 and October 2023 and 35 control groups with similar age and gender were prospectively included in the study. The TTSS of the patient group was calculated at the time of presentation, and changes in TTSS-related amino acid levels were evaluated in blood samples taken from the patient and control groups.
Conclusion: It is hypothesised that the determination of amino acid levels, including arginine, glycine and taurine, and the replacement of absent values will facilitate the recuperation of patients, enhancing vital functions following trauma and reducing or eliminating mortality.

Keywords : Trauma, thoracic trauma, amino acid, thoracic trauma severity score, emergency department

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Article available in :
Volume 5, Issue 4, 2025
Page : 221-226
https://doi.org/10.51271/KMJ-0215
Article Information
Received : 31 Ara 2024
Accepted : 05 Mar 2025
Published : 02 Ara 2025
Corresponding Author :

Onur Türkdoğan: Department of Emergency Medicine, Faculty of Medicine, Sivas Cumhuriyet University, Sivas, Turkiye

[email protected]
Citation : Türkdoğan O, Tekin YK, Korkmaz İ, et al. Determine the relationship between the severity of trauma and plasma amino acid levels in patients presenting to the emergency department after isolated thoracic trauma. Kastamonu Med J. 2025;5(4):221-226.

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